Endoscopic resection of small-bowel submucosal nodule.

The options for management of submucosal nodules in the small bowel are limited. A 67-year-old woman presented for evaluation after positive findings from fecal immunochemical testing. Colonoscopy showed a 2-cm submucosal nodule in the terminal ileum. Superficial biopsies from the lesion were unrevealing. Over-thescope clip (OTSC)-assisted resection was planned. An OTSC (size 12/6, type gc) was applied to the base of the lesion and hot snare resection was performed above the clip (●" Fig.1, ●" Video 1). The collected tissue was submitted for pathological examination, which showed lipoma. No procedure-related complications were seen. We conclude that OTSC-assisted resection is a safe management option for submucosal nodules in the small intestine.